| Gene Symbol | CFTR |
| Chromosome | 7q31.2 |
| Protein Type | Transporter |
| Function | encodes a member of the ATP-binding cassette (ABC) transporter superfamily that functions as a cAMP-activated chloride channel. |
| Primary Expression | the central nervous system where it plays important roles in neuronal function, astrocytic homeostasis, and neuroinflammation[@guggino2014] |
| Molecular Weight | 168 kDa |
| Amino Acids | 480 aa |
| Pathways | Akt, Autophagy, Calcium Signaling, Mapk, Mtor |
| UniProt ID | P13569 |
| NCBI Gene ID | 1080 |
| Ensembl ID | ENSG00000001626 |
| OMIM | 602421 |
| GeneCards | CFTR |
| Human Protein Atlas | CFTR |
| Associated Diseases | Als, Cancer, Copd, Cystic Fibrosis, Fibrosis, Hypertension |
| Interactions | AKT1, AKT1S1, AMPK, ATG, ATP, AUTOPHAGY |
| KG Connections | 425 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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