disease

Copd

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Copd: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

436Connections
0Hypotheses
0Analyses
45Outgoing
50Incoming

No summary available yet. View on Wiki →

Disease Info
Associated GenesPAH, ATG, ROS, AUTOPHAGY, TNF, CFTR, TGFB1, MAP1LC3B
Therapeutic AgentsByf
KG Connections127 knowledge graph edges
DatabasesOMIMOrphanetClinicalTrialsPubMed

Wiki Pages (20)

Knowledge base pages for this entity

SERPINA3 Gene — Alpha-1 Antichymotrypsin in Neurodegeneration

gene · 3284 words

Lupin Pharmaceuticals

company · 3175 words

NIH Drug Repurposing Program for Neurodegenerative Diseases

institution · 3160 words

jnk-p38-mapk-parkinsons

mechanism · 3111 words

Utilisation of Health Services and Quality of Life in Atypical Parkinsonian Syndromes (NCT06645626)

clinical · 3029 words

Pathway Diagram

graph TD
    Copd["Copd"] -->|"activates"| Als["Als"]
    Copd["Copd"] -->|"activates"| Inflammation["Inflammation"]
    Copd["Copd"] -->|"regulates"| Als_1["Als"]
    Copd["Copd"] -->|"therapeutic target"| Inflammation_2["Inflammation"]
    Copd["Copd"] -.->|"inhibits"| Pi3K_Akt["Pi3K/Akt"]
    Copd["Copd"] -->|"causes"| Oxidative_Stress["Oxidative Stress"]
    Byf["Byf"] -->|"treats"| Copd["Copd"]
    INFLAMMATION["INFLAMMATION"] -->|"activates"| Copd["Copd"]
    INFLAMMATION_3["INFLAMMATION"] -->|"therapeutic target"| Copd["Copd"]
    INFLAMMATION_4["INFLAMMATION"] -->|"regulates"| Copd["Copd"]
    style Copd fill:#ef5350,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (173)

TargetRelationTypeStr
Alsactivatesdisease0.85
Inflammationactivatesdisease0.75
Alsregulatesdisease0.75
Inflammationtherapeutic_targetdisease0.75
Pi3K/Aktinhibitspathway0.70

Incoming (263)

SourceRelationTypeStr
Byftreatsdrug0.95
INFLAMMATIONactivatesgene0.85
INFLAMMATIONtherapeutic_targetgene0.85
INFLAMMATIONregulatesgene0.75
AKTinhibitsgene0.75

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found