Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FRAILTY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | FRAILTY |
| Key Genes/Proteins | C1Q |
| Related Diseases | Age-Related Diseases |
| Related Pathways | INFLAMMATION |
Knowledge base pages for this entity
graph TD
FRAILTY["FRAILTY"]
FRAILTY -->|"risk_factor_for"| Mortality["Mortality"]
FRAILTY -->|"risk_factor_for"| Disease["Disease"]
Inflammation["Inflammation"] -.biomarker for.-> FRAILTY
Cxcl10["Cxcl10"] -.biomarker for.-> FRAILTY
Il6["Il6"] -.biomarker for.-> FRAILTY
Cx3Cl1["Cx3Cl1"] -.biomarker for.-> FRAILTY
Gdf15["Gdf15"] -.biomarker for.-> FRAILTY
Mitochondrial_Dysfunction["Mitochondrial Dysfunction"] -->|"contributes to"| FRAILTY
Physical_Exercise["Physical Exercise"] -->|"treats"| FRAILTY| Target | Relation | Type | Str |
|---|---|---|---|
| Mortality | risk_factor_for | phenotype | 0.90 |
| Disease | risk_factor_for | disease | 0.85 |
| Biomarkers | correlates_with | biomarker | 0.75 |
| Source | Relation | Type | Str |
|---|---|---|---|
| INFLAMMATION | associated_with | pathway | 0.90 |
| Age-Related Diseases | risk_factor_for | disease | 0.90 |
| OXIDATIVE STRESS | implicated_in | process | 0.80 |
| C1Q | associated_with | protein | 0.56 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||