gene 3,783 words KG: GBA
Contents

GBA Gene

🧬 Gene Info
Gene SymbolGBA
Functionis a critical gene in the intersection of lysosomal storage disorders and neurodegenerative diseases.
Molecular Weight60 kDa
Amino Acids536 aa
PathwaysAmyloid, Autophagy, Autophagy-Lysosomal Pathway, Chaperone, Epigenetic
Ensembl IDENSG00000177628
GeneCardsGBA
Human Protein AtlasGBA
Associated DiseasesAD, ALI, ALS, Aging, Alzheimer
InteractionsFUNDC1, AMBRA1, PINK1, BCL2L13, NLRP3, ABCD3
KG Connections1489 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Experiments (2)

Validate Mitochondria-Lysosome Contact Site Dysfunction in P
validation · proposed · Score: 0.40
LRRK2/GBA Mutation Carrier Resilience — Why Some Carriers Ne
validation · proposed · Score: 0.40

Knowledge Graph (12 edges)

GBA interacts_with FUNDC1
GBA interacts_with AMBRA1
GBA interacts_with PINK1
GBA interacts_with BCL2L13
GBA interacts_with NLRP3
GBA interacts_with ABCD3
GBA interacts_with FIP200
GBA interacts_with RTN3
GBA interacts_with SESN2
GBA associated_with PLIN2