gene 2,340 words KG: CTSB
Contents

CTSB Gene

🧬 Gene Info
Gene SymbolCTSB
Full NameCathepsin B
Chromosome8p23.1
Subcellular Localization| Compartment | Function |
Molecular Weight26 kDa
Amino Acids339 aa
Exons13
PathwaysAutophagy
UniProt IDP07846
NCBI Gene ID1508
Ensembl IDENSG00000164733
OMIM116810
GeneCardsCTSB
Human Protein AtlasCTSB
Associated DiseasesAging, Als, Alzheimer, Amyotrophic Lateral Sclerosis, APOPTOSIS
Known Drugs/Compoundsrapamycin, tannic acid
InteractionsACTB, Actin, AGING, AIF1, AKT, ALS
SciDEX HypothesesSelective cathepsin B inhibition prevents cathepsi
KG Connections815 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

Lysosomal Acidification Failure: Convergent GBA1/LAMP2A–medi
Score: 0.70
Selective cathepsin B inhibition prevents cathepsin leakage-
Score: 0.62

Knowledge Graph (12 edges)

CTSB activates C1QA
CTSB activates SPP1
CTSB activates GRN
STIP1 associated_with CTSB
LGALS3 associated_with CTSB
HSPA8 associated_with CTSB
MCOLN1 associated_with CTSB
SQSTM1 associated_with CTSB
SOD1 associated_with CTSB
BCL2 associated_with CTSB

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