| Gene Symbol | HIF |
| Full Name | Hypoxia Inducible Factor 1 Subunit Alpha |
| Chromosome | 14q21.1 |
| Function | PHD inactivation: Reduced prolyl hydroxylation |
| Pathways | Aerobic Glycolysis, Akt, Autophagy, Epigenetic, Immune Response |
| UniProt ID | Q16665 |
| NCBI Gene ID | 3091 |
| Ensembl ID | ENSG00000100644 |
| OMIM | 603348 |
| GeneCards | HIF |
| Human Protein Atlas | HIF |
| Associated Diseases | AD, ALI, Als, Alzheimer, ATHEROSCLEROSIS |
| Known Drugs/Compounds | daprodustat, roxadustat |
| Interactions | ABCD3, acetylcholine, ACHE, AD, AGING, AKT |
| SciDEX Hypotheses | HIF1A stabilization lowers the activation threshol Moderate hyperoxia (1.5-2.0 ATA) optimally stabili |
| KG Connections | 1193 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!