| Gene Symbol | ATXN3 |
| Full Name | Ataxin-3 |
| Aliases | SCA3/Machado-Joseph Disease |
| Chromosome | 14q32.12 |
| Protein Type | Protease |
| Function | Polyubiquitin chain cleavage — Preferentially cleaves K63-linked chains |
| Molecular Weight | 42 kDa |
| Amino Acids | 364 aa |
| Pathways | Autophagy |
| UniProt ID | P54252 |
| GeneCards | ATXN3 |
| Human Protein Atlas | ATXN3 |
| Associated Diseases | ALS, Alzheimer's disease, Ataxia, Huntington's disease, Ms |
| Interactions | BMAL1, PER2, IRF1, STAT3, SCA3, G3BP1 |
| KG Connections | 162 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |