| Gene Symbol | FGFR3 |
| Full Name | Fibroblast Growth Factor Receptor 3 |
| Aliases | Page for FGFR3 |
| Chromosome | 4p16.3 |
| Protein Family | FGFR tyrosine kinase family |
| Protein Type | Receptor |
| Function | FGFR3 (Fibroblast Growth Factor Receptor 3) is a receptor tyrosine kinase that binds FGFs. |
| Primary Expression | chondrocytes where it negatively regulates bone growth, explaining why activating FGFR3 mutations cause achondroplasia, the most common form of dwarfi |
| Molecular Weight | 88.5 kDa |
| Amino Acids | 808 aa |
| Exons | 19 |
| Pathways | MAPK, PI3K |
| UniProt ID | P22607 |
| GeneCards | FGFR3 |
| Human Protein Atlas | FGFR3 |
| Associated Diseases | Als, Breast Cancer, Cancer, Carcinoma, Inflammation, Pancreatic Cancer |
| Interactions | TP53, RB1, TCF3, EP300, BMPR1A, OVERVIEW |
| KG Connections | 98 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |