| Gene Symbol | KDM6A |
| Full Name | KDM6A |
| Aliases | Lysine Specific Demethylase 6A (UTX), Lysine Specific Demethylase 6A (UTX |
| Protein Type | Epigenetic Regulator |
| Target Class | Epigenetic Regulator |
| Function | Small molecule inhibition of histone demethylase activity |
| Mechanism of Action | Small molecule inhibition of histone demethylase activity |
| Druggability | Low (0.35) |
| Clinical Stage | Phase I |
| Molecular Weight | 160 kDa |
| Amino Acids | 401 aa |
| Exons | 29 |
| Pathways | Epigenetic |
| UniProt ID | A0A087X0R0 |
| NCBI Gene ID | Search NCBI |
| GeneCards | KDM6A |
| Human Protein Atlas | KDM6A |
| Associated Diseases | OXIDATIVE STRESS, SYNAPTIC PLASTICITY, cancer, inflammation, neurodegeneration |
| Known Drugs/Compounds | GSK-J4 |
| Interactions | PI3K, GBM, MTOR, TP53, BRCA2, ATM |
| SciDEX Target | View Target Profile (8 clinical trials) |
| SciDEX Hypotheses | KDM6A-Mediated H3K27me3 Rejuvenation |
| KG Connections | 153 knowledge graph edges |
| Databases | GeneCardsHPASTRING |