| Gene Symbol | MC4R |
| Full Name | Melanocortin 4 Receptor |
| Aliases | MC4R gene encoding the melanocortin 4 receptor |
| Chromosome | 18q21.3 |
| Protein Type | Receptor |
| Function | encodes a G protein-coupled receptor (GPCR) that plays a critical role in energy homeostasis, appetite regulation, and metabolic function. |
| Primary Expression | the central nervous system and regulates food intake, energy expenditure, and body weight |
| Molecular Weight | ~37 kDa |
| Amino Acids | 332 aa |
| UniProt ID | P32246 |
| NCBI Gene ID | 4162 |
| Ensembl ID | ENSG00000137273 |
| OMIM | 601665 |
| GeneCards | MC4R |
| Human Protein Atlas | MC4R |
| Associated Diseases | Als, Obesity, neurodegeneration |
| Interactions | NLRP3, NR3C2, HDAC6, BDNF, CNR1, DRD1 |
| KG Connections | 36 knowledge graph edges |
| Databases | GeneCardsHPASTRING |