| Gene Symbol | UCP2 |
| Full Name | Uncoupling Protein 2 |
| Chromosome | 11q13.4 |
| Protein Type | Protein |
| Function | UCP2 is a mitochondrial anion carrier protein that uncouples oxidative phosphorylation: |
| Amino Acids | 309 aa |
| Pathways | AMPK |
| UniProt ID | Search UniProt |
| GeneCards | UCP2 |
| Human Protein Atlas | UCP2 |
| AMP-activated protein kinase (AMPK) | Energy deficit activates AMPK, promoting UCP2 expression. |
| Sirtuins (SIRT1/SIRT2) | NAD+-dependent deacetylases regulate UCP2 under metabolic stress conditions. |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, ALS |
| Interactions | AGING, AIM2, AMPK, AND, APOPTOSIS, ASC |
| KG Connections | 104 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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