gene 1,003 words KG: VGF 2026-03-21
kind:genesection:genesstate:published
Contents

VGF — VGF Nerve Growth Factor Inducible

🧬 Gene Info
Gene SymbolVGF
Full NameVGF Nerve Growth Factor Inducible
Chromosome7q22.1
Primary Expressionneurons of the central and peripheral nervous systems
Molecular Weight68 kDa
Amino Acids617 aa
PathwaysMAPK pathway, PI3K, AMPK pathway
UniProt IDQ9Y241
NCBI Gene ID9005
Ensembl IDENSG00000149716
OMIM607416
GeneCardsVGF
Human Protein AtlasVGF
RegionExpression Level
HypothalamusVery High
Associated DiseasesAD, ALI, Als, Alzheimer, Alzheimer'S Disease
InteractionsHDAC1, NTRK2, BDNF, NGF, CTSB, CTSD
KG Connections118 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Netrin-1 Gradient Restoration
Score: 0.33

Related Analyses (3)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (12)

Packard Center for ALS Research
institution · KG edge: activates
Accelerating Medicines Partnership for Alzheimer's Dise
institution · KG edge: implicated_in
Alzheimer Indonesia
institution · KG edge: associated_with
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: expressed_in
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: associated_with

Knowledge Graph (12 edges)

VGF associated_with NTN1
VGF associated_with GPNMB
VGF associated_with NPTX2
VGF activates HDAC1
VGF regulates AKT
VGF regulates DISC1
VGF activates NTRK2
VGF activates BDNF
VGF activates NGF
VGF regulates BDNF