protein 757 words KG: VGF 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

VGF Nerve Growth Factor

🔬 Protein Info
Gene SymbolVGF
Chromosome7q22.1
Primary Expressionneurons of the central and peripheral nervous systems
Molecular Weight68 kDa
Amino Acids617 aa
PathwaysMAPK pathway, PI3K, AMPK pathway
UniProt IDQ9UK23
NCBI Gene ID5139
GeneCardsVGF
Human Protein AtlasVGF
PeptideSequence
TLQP-62TLQPDSGHFPQPF
AQEE-30AQEELHSGFDQRY
LQEQ-19LQEQELHRLQEF
Associated DiseasesAD, ALI, Als, Alzheimer, Alzheimer'S Disease
InteractionsHDAC1, NTRK2, BDNF, NGF, CTSB, CTSD
KG Connections118 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35
Netrin-1 Gradient Restoration
Score: 0.33

Related Analyses (4)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (10)

Alzheimer Indonesia
institution · KG edge: associated_with
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: expressed_in
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: associated_with
HSPA1A Gene
gene · KG edge: activates
GPNMB Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

VGF associated_with NTN1
VGF associated_with GPNMB
VGF associated_with NPTX2
VGF activates HDAC1
VGF regulates AKT
VGF regulates DISC1
VGF activates NTRK2
VGF activates BDNF
VGF activates NGF
VGF regulates BDNF