gene 649 words KG: VPS13C 2026-03-21
kind:genesection:genesstate:published
Contents

VPS13C Gene - Vacuolar Protein Sorting 13 Homolog C

🧬 Gene Info
Gene SymbolVPS13C
Full NameVacuolar Protein Sorting 13 Homolog C
AliasesPage for VPS13C Gene
Chromosome15q22.31
FunctionVPS13C is a member of the VPS13 family of lipid-transfer proteins.
Molecular Weight395 kDa
Amino Acids100 aa
Exons77
PathwayscGAS-STING pathway
UniProt IDQ9UPQ0
NCBI Gene ID86728
Ensembl IDENSG00000129048
GeneCardsVPS13C
Human Protein AtlasVPS13C
Associated DiseasesAls, Alzheimer, Ms, Parkinson, Parkinson's disease
InteractionsATP13A2, DNAJC6, FBXO7, PINK1, PLA2G6, PRKN
KG Connections71 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Membrane Cholesterol Gradient Modulators
Score: 0.52
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.51
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.49

Related Analyses (7)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

LRRK2 G2019S Transgenic Mouse Model
model · KG edge: associated_with
Mitophagy Receptor Pathway in Neurodegeneration
mechanism · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
TARDBP — TAR DNA Binding Protein 43
gene · KG edge: associated_with

Knowledge Graph (12 edges)

VPS13C encodes lipid transfer protein
VPS13C activates mitochondrial DNA accumulation
VPS13C associated_with BNIP3L
VPS13C associated_with MAP1LC3B
VPS13C associated_with DNAJC6
VPS13C associated_with ATP13A2
VPS13C associated_with PLA2G6
VPS13C associated_with PRKN
VPS13C associated_with ATP1A3
VPS13C associated_with SNCA