gene 1,513 words KG: ISG15
Contents

ISG15 — Interferon-Stimulated Gene 15

🧬 Gene Info
Gene SymbolISG15
Full NameInterferon-Stimulated Gene 15
Chromosome1p36.33
Functionis a ubiquitin-like protein that is induced by type I interferons (IFN-α/β) and plays a critical role in the innate immune response.
Amino Acids165 aa
Exons2
PathwaysAkt, Autophagy, Lipid Metabolism, Mapk, Pi3K
UniProt ID[P51959](https://www.uniprot.org/uniprot/P51959)
Ensembl IDENSG00000187608
OMIM607117
GeneCardsISG15
Human Protein AtlasISG15
Associated DiseasesAls, Alzheimer Disease, Cancer, Cognitive Deficits, Depression, Inflammation
InteractionsAKT, ALZHEIMER, ALZHEIMER DISEASE, ASC, ASK1, ATF3
KG Connections271 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

ISG15 participates_in INTERFERON_RESPONSE
CSF2 regulates ISG15
NAMPT regulates ISG15
FGF2 regulates ISG15
CXCL10 activates ISG15
HSPA1A regulates ISG15
FGF8 regulates ISG15
TLR4 regulates ISG15
ISG15 activates STAT1
ISG15 regulates CSF2RA

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