gene 1,116 words KG: LITAF 2026-03-29
kind:genesection:genesstate:published
Contents

LITAF — Lipopolysaccharide-Induced Tumor Necrosis Factor Factor

🧬 Gene Info
Gene SymbolLITAF
Full NameLipopolysaccharide-Induced Tumor Necrosis Factor Factor
AliasesSIMPLE, CMT1C
Chromosome16p13.13
FunctionThe protein contains several functional domains
Subcellular Localizationthe lysosomal membrane and late endosome compartments. The protein contains several functional domains:
Molecular Weight17 kDa
Amino Acids161 aa
PathwaysAutophagy, Cell Cycle, Immune Response, Mtor
UniProt IDQ9Y5K2
NCBI Gene ID10868
Ensembl IDENSG00000106789
OMIM604577
GeneCardsLITAF
Human Protein AtlasLITAF
Associated DiseasesALS, Alzheimer's disease, frontotemporal dementia
InteractionsSOX2, IRF1, SOX9, NFKBIA, JUN, Nfkb
KG Connections75 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

LITAF regulates IL6R
LITAF regulates MERTK
LITAF regulates DUSP1
LITAF regulates ADCY9
LITAF activates SOX2
LITAF regulates CDKN1A
LITAF regulates SESN1
LITAF activates IRF1
LITAF regulates NDRG2
LITAF activates SOX9

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