gene 1,509 words KG: MAPK8
Contents

MAPK8 Gene

🧬 Gene Info
Gene SymbolMAPK8
Full NameMitogen-Activated Protein Kinase 8
Chromosome10q11.22.
Protein FamilyMAPK (Mitogen-Activated Protein Kinases)
Protein TypeSerine/Threonine Kinase
Function- Transcription factors: c-Jun, JunB, JunD, ATF2, ELK-1
Molecular Weight46 kDa
Amino Acids427 aa
PathwaysMAPK, NF-κB
UniProt IDP45985
NCBI Gene ID5599
Ensembl IDENSG00000106789
GeneCardsMAPK8
Human Protein AtlasMAPK8
Associated DiseasesAD, Aging, ALI, Als, Alzheimer
Known Drugs/CompoundsPolyphenols, rapamycin
InteractionsABCD3, AKT1, ALS, ALZHEIMER, ALZHEIMER DISEASE, AMBRA1
KG Connections634 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

A lower-dose 50-100 mg/day glial anti-inflammatory effect ma
Score: 0.48

Knowledge Graph (12 edges)

CAT interacts_with MAPK8
OPTN interacts_with MAPK8
DNM1L interacts_with MAPK8
CANX interacts_with MAPK8
LGALS3 interacts_with MAPK8
CALCOCO2 interacts_with MAPK8
G3BP1 interacts_with MAPK8
PEX3 interacts_with MAPK8
SQSTM1 interacts_with MAPK8
BCL2 interacts_with MAPK8

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