gene 668 words KG: MFN1
Contents

Mitofusin 1 (MFN1)

🧬 Gene Info
Gene SymbolMFN1
Chromosome3q26.33
FunctionMitofusin 1 (MFN1) is a dynamin-like GTPase essential for mitochondrial outer membrane fusion
Primary Expressionhippocampus, Cerebellum, Cortex, Striatum, Substantia Nigra
Molecular Weight83 kDa
PathwaysApoptosis, Autophagy, Epigenetic, Lysosomal Degradation, Mitochondrial Function
GeneCardsMFN1
Human Protein AtlasMFN1
Associated DiseasesAD, ALI, Als, Alzheimer, COPD
InteractionsABCD3, Actin, AGING, AKT, ALS, ALZHEIMER
KG Connections921 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

DRP1 S616 Hyperphosphorylation and MFN2 Downregulation Creat
Score: 0.68
OPA1-Mediated Cristae Architecture Vulnerability
Score: 0.49

Knowledge Graph (12 edges)

CAT interacts_with MFN1
OPTN interacts_with MFN1
DNM1L interacts_with MFN1
CANX interacts_with MFN1
LGALS3 interacts_with MFN1
CALCOCO2 interacts_with MFN1
G3BP1 interacts_with MFN1
PEX3 interacts_with MFN1
SQSTM1 interacts_with MFN1
BCL2 interacts_with MFN1

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