gene 1,538 words KG: NGF
Contents

NGF Gene

🧬 Gene Info
Gene SymbolNGF
Full NameNerve Growth Factor
Chromosome1p13.1
Protein FamilyNeurotrophin family
Primary ExpressionPrimarily in nociceptive sensory neurons, cholinergic basal forebrain neurons, sympathetic ganglia
Molecular Weight30 kDa
Amino Acids120 aa
Exons3
PathwaysPI3K, MAPK
UniProt IDP01138
NCBI Gene ID4800
Ensembl IDENSG00000111665
OMIM162030
GeneCardsNGF
Human Protein AtlasNGF
Associated DiseasesAls, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis, ANGIOGENESIS
Known Drugs/Compoundsaducanumab, lecanemab, metformin
InteractionsACHE, Actin, ADRB2, AGING, Akt, AKT
KG Connections763 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

Basal forebrain NGF/TrkA trophic failure is an upstream trig
Score: 0.61
Gamma Restoration Reduces Tau via Glymphatic Clearance
Score: 0.28

Knowledge Graph (12 edges)

NGF activates CHR2
NGF activates BDNF
TRKA interacts_with NGF
NRP1 activates NGF
NGF inhibits GAIN
MTOR inhibits NGF
NGF activates DCX
NGF expressed_in BDNF
NGF activates HES1
NGF activates NESTIN

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