protein 865 words KG: OVERVIEW 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

Proteins Overview

🔬 Protein Info
Gene SymbolOVERVIEW
PathwaysAdaptive Immunity, Akt, Angiogenesis, Apoptosis, Autophagy
GeneCardsOVERVIEW
Human Protein AtlasOVERVIEW
CategoryKey Proteins
AggregationAPP, Tau, α-syn, TDP-43
SynapticSynaptophysin, PSD-95, NMDA-R
InflammatoryTREM2, CD33, IL-1β
TransportDynein, Kinesin
TranscriptionTDP-43, FUS
ChaperonesHsp70, Hsp90
Associated DiseasesALS, Addiction, Aging, Alzheimer, Alzheimer'S Disease
InteractionsVALOSIN, CHMP2B, TARDBP, LC3, TBK1, GAIN
KG Connections2317 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (30)

Synthetic Biology Approach: Designer Mitochondrial Export Sy
Score: 0.36
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
Adenosine-Astrocyte Metabolic Reset
Score: 0.56
SASP-Mediated Complement Cascade Amplification
Score: 0.70

Related Analyses (24)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (7)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
ADORA2A Gene
gene · KG edge: regulates
adam17
gene · KG edge: implicated_in
Synthetic Lethality and PARP Inhibition in Neurodegener
mechanism · Pages share 3 hypotheses
Quantum Biology and Coherent Energy Transfer in Neurode
mechanism · Pages share 3 hypotheses

Knowledge Graph (12 edges)

OVERVIEW biomarker_for BRAF
OVERVIEW biomarker_for ATRX
OVERVIEW activates VALOSIN
OVERVIEW therapeutic_target CXCR1
OVERVIEW regulates LETM1
OVERVIEW regulates MCU
OVERVIEW activates CHMP2B
OVERVIEW activates TARDBP
OVERVIEW activates LC3
OVERVIEW activates TBK1