protein 732 words KG: RANKINGS 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

Protein Rankings

🔬 Protein Info
Gene Symbolrankings
PathwaysInsulin Signaling, Akt, Mapk, Pi3K
RankProtein
1TDP-43
2FUS
3SOD1
4Parkin
5PINK1
6DJ-1
7VPS35
8Synphilin-1
9GSN (Gelsolin)
10ATP13A2 (PARK9)
Associated DiseasesLymphoma
InteractionsRAC1, PI3K, AKT, RHOA, TRAF2, TRAF6
KG Connections25 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (20)

Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
TREM2-Dependent Microglial Senescence Transition
Score: 0.69
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54

Related Analyses (6)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

See Also (14)

MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: associated_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: interacts_with
Packard Center for ALS Research
institution · KG edge: interacts_with
TGFBR1 — TGF-beta Receptor 1
gene · KG edge: interacts_with
RHOA Gene — Ras Homolog Family Member A
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

RANKINGS interacts_with RAC1
RANKINGS associated_with MAPK1
RANKINGS interacts_with PI3K
RANKINGS associated_with CBL
RANKINGS interacts_with AKT
RANKINGS interacts_with RHOA
RANKINGS interacts_with TRAF2
RANKINGS interacts_with TRAF6
RANKINGS interacts_with TGFBR1
RANKINGS associated_with PTEN