Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,499 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,499)🧬 gene (3,870)🔬 cell (3,397)🔬 protein (3,108)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (498)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (139) entity (114)
Showing 1–50 of 69 pages matching "glutamate"

🧬 GRIK3 - Glutamate Receptor Kainate Type Subunit 3KG

gene · 2,977 words · 2 hyp4 ana1 exp

⚙️ Glutamate Excitotoxicity Pathway in NeurodegenerationKG

mechanism · 2,827 words · 302 hyp58 ana56 exp

🧬 GRID1 — Glutamate Ionotropic Receptor Delta Type Subunit 1KG

gene · 2,567 words · 1 hyp2 ana12 exp

🔬 mGluR5 Metabotropic Glutamate NeuronsKG

cell · 2,406 words · 6 hyp11 ana1 exp

glutamateKG

general · 2,389 words · 71 hyp50 ana8 exp

🔬 mGluR2 Protein — Glutamate Metabotropic Receptor 2KG

protein · 2,220 words · 6 hyp9 ana1 exp

⚙️ Glutamate Excitotoxicity in NeurodegenerationKG

mechanism · 2,206 words · 303 hyp58 ana59 exp

💊 EAAT2 Glutamate Transporter Rescue TherapyKG

therapeutic · 2,079 words · 40 hyp21 ana2 exp

🔬 Metabotropic Glutamate Receptor 7 (mGluR7) NeuronsKG

cell · 1,969 words · 12 hyp16 ana1 exp

🧬 GRID2 — Glutamate Ionotropic Receptor Delta Type Subunit 2KG

gene · 1,942 words · 2 hyp3 ana12 exp

⚙️ Glutamatergic Signaling PathwayKG

mechanism · 1,844 words · 60 hyp38 ana3 exp

🔬 Glutamatergic Neurons — Cell Type HierarchyKG

cell · 1,819 words · 7 hyp12 ana2 exp

Glutamate Receptor NeuronsKG

cell_type · 1,797 words · 274 hyp54 ana1 exp

💡 Astrocyte Glutamate-Buffer Rescue: EAAT2 Transcription Reboot TherapyKG

idea · 1,794 words · 131 hyp61 ana16 exp

🔬 Ventral Tegmental Area Glutamatergic NeuronsKG

cell · 1,745 words · 7 hyp12 ana6 exp

🧬 GRM5 Gene - Metabotropic Glutamate Receptor 5KG

gene · 1,738 words · 4 hyp6 ana1 exp

🔬 Subthalamic Nucleus Glutamatergic NeuronsKG

cell · 1,625 words · 6 hyp11 ana4 exp

⚙️ PSP Excitotoxicity and Glutamatergic DysfunctionKG

mechanism · 1,585 words · 8 hyp37 ana24 exp

💡 Astrocyte Glutamate-Buffer Rescue with EAAT2 Transcription RebootKG

idea · 1,556 words · 120 hyp59 ana15 exp

📊 Glutamate - Excitotoxicity and Neurodegeneration BiomarkerKG

biomarker · 1,499 words · 296 hyp54 ana55 exp

🧬 GRIP3 (Glutamate Receptor Interacting Protein 3)KG

gene · 1,493 words · 5 hyp8 ana3 exp

🔬 GRIP2 Protein - Glutamate Receptor Interacting Protein 2KG

protein · 1,489 words · 5 hyp9 ana3 exp

🔬 mGluR8 Protein (Metabotropic Glutamate Receptor 8)KG

protein · 1,429 words · 6 hyp9 ana1 exp

⚙️ Glutamate TransportKG

mechanism · 1,426 words · 92 hyp60 ana5 exp

🔬 mGluR7 Protein (Metabotropic Glutamate Receptor 7)KG

protein · 1,418 words · 5 hyp9 ana1 exp

🔬 Metabotropic Glutamate Receptor 1 (mGluR1) NeuronsKG

cell · 1,330 words · 10 hyp13 ana1 exp

🔬 mGluR6 Protein (Metabotropic Glutamate Receptor 6)KG

protein · 1,246 words · 5 hyp9 ana1 exp

⚙️ Glutamate Signaling PathwayKG

mechanism · 1,212 words · 126 hyp60 ana1 exp

🔬 GRIK3 Protein - Glutamate Receptor Kainate Type Subunit 7KG

protein · 1,197 words · 5 hyp9 ana1 exp

🔬 Metabotropic Glutamate (mGluR) Receptor NeuronsKG

cell · 1,105 words · 10 hyp13 ana1 exp

🧬 GRIK1 - Glutamate Receptor Kainate Type Subunit 1KG

gene · 1,088 words · 2 hyp4 ana1 exp

🧬 GLUD1 - Glutamate Dehydrogenase 1KG

gene · 1,083 words · 5 hyp3 ana5 exp

🔬 mGluR5 (Metabotropic Glutamate Receptor 5)KG

protein · 1,067 words · 4 hyp5 ana1 exp

🔬 mGluR3 Protein — Glutamate Metabotropic Receptor 3KG

protein · 1,066 words · 6 hyp9 ana1 exp

🧬 GRIP1 — Glutamate Receptor Interacting Protein 1KG

gene · 1,036 words · 5 hyp10 ana3 exp

🔬 Vesicular Glutamate Transporter (VGLUT) NeuronsKG

cell · 1,029 words · 6 hyp12 ana2 exp

🧬 GRIK4 - Glutamate Receptor Kainate Type Subunit 4KG

gene · 971 words · 4 hyp4 ana1 exp

🔬 mGluR4 Protein — Glutamate Metabotropic Receptor 4KG

protein · 947 words · 6 hyp9 ana1 exp

🔬 Subthalamic Nucleus Glutamate NeuronsKG

cell · 940 words · 5 hyp11 ana3 exp

🔬 Metabotropic Glutamate Receptor 8 (mGluR8) NeuronsKG

cell · 935 words · 9 hyp13 ana1 exp

🔬 GRIK4 Protein - Glutamate Receptor Kainate Type Subunit 8KG

protein · 928 words · 5 hyp9 ana1 exp

🧬 GRIK5 - Glutamate Receptor Kainate Type Subunit 5KG

gene · 924 words · 2 hyp4 ana1 exp

🔬 Metabotropic Glutamate Receptor 2 (mGluR2) NeuronsKG

cell · 923 words · 9 hyp14 ana1 exp

🧬 Glutamate Decarboxylase 2KG

gene · 917 words · 6 hyp3 ana7 exp

🧬 Glutamate Decarboxylase 1KG

gene · 914 words · 8 hyp4 ana4 exp

🔬 Metabotropic Glutamate Receptor 4 (mGluR4) NeuronsKG

cell · 912 words · 9 hyp13 ana1 exp

🧬 GCLM — Glutamate-Cysteine Ligase Modifier SubunitKG

gene · 910 words · 1 ana2 exp

💊 Metabotropic Glutamate Receptor Modulator Therapy for NeurodegenerationKG

therapeutic · 889 words · 286 hyp48 ana56 exp

🔬 GRIK1 Protein - Glutamate Receptor Kainate Type Subunit 5KG

protein · 882 words · 5 hyp9 ana1 exp

🧬 GRM3 — Glutamate Metabotropic Receptor 3KG

gene · 867 words · 6 hyp5 ana1 exp

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