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SMPD1 Gene - Acid Sphingomyelinase

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-smpd1
Related Entities
SMPD1
Metadata
sluggenes-smpd1
entity_typegene
kg_node_idSMPD1
🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

Linked Artifacts (98)
mentions🧪Selective Acid Sphingomyelinase Modulation Therapy90%
targets🧪Selective Acid Sphingomyelinase Modulation Therapy90%
analysis_target🔬Investigate how lipid raft composition (cholesterol metaboli80%
mentions🧪Selective Acid Sphingomyelinase Modulation Therapy80%
related🧪Selective Acid Sphingomyelinase Modulation Therapy80%
related🧪Selective Acid Sphingomyelinase Modulation Therapy80%
mentions🔬Investigate how lipid raft composition (cholesterol metaboli70%
mentions🧫Experiment: Multi-Ethnic PD GWAS70%
mentions📓Selective Acid Sphingomyelinase Modulation Therapy -- Comput70%
related🧫Animal Model Comparison for Neurodegenerative Disease Therap70%
related🧫Endocannabinoid System Dysfunction Validation in Parkinson&#70%
related🧫Glymphatic-Circadian Axis Enhancement Therapy for Parkinson&70%
related🧫Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag70%
related🧫Neural Oscillation Dysfunction Validation in Parkinson'70%
related🧫Oligodendrocyte-Myelin Dysfunction Validation in Parkinson&#70%
related🧫Proteasome-Ubiquitin System Dysfunction Validation in Parkin70%
related🧫Protein Aggregation Kinetic Validation Results70%
related🧫Purinergic Signaling Dysfunction Validation in Parkinson70%
related🧫Regulated Necrosis Validation Study in Parkinson's Dise70%
related🧫Stress Granule Dysfunction Validation in Parkinson's Di70%
related🧫Experiment Validation: In vitro ThT Assay70%
related🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas70%
related🔬Investigate how lipid raft composition (cholesterol metaboli70%
related🧫Animal Model Comparison for Neurodegenerative Disease Therap70%
related🧫Endocannabinoid System Dysfunction Validation in Parkinson&#70%
related🧫Glymphatic-Circadian Axis Enhancement Therapy for Parkinson&70%
related🧫Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag70%
related🧫Neural Oscillation Dysfunction Validation in Parkinson'70%
related🧫Oligodendrocyte-Myelin Dysfunction Validation in Parkinson&#70%
related🧫Proteasome-Ubiquitin System Dysfunction Validation in Parkin70%
related🧫Protein Aggregation Kinetic Validation Results70%
related🧫Purinergic Signaling Dysfunction Validation in Parkinson70%
related🧫Regulated Necrosis Validation Study in Parkinson's Dise70%
related🧫Stress Granule Dysfunction Validation in Parkinson's Di70%
related🧫Experiment Validation: In vitro ThT Assay70%
see_also🧪Selective Acid Sphingomyelinase Modulation Therapy70%
see_also📓Selective Acid Sphingomyelinase Modulation Therapy -- Comput70%
mentions🔬Investigate how lipid raft composition (cholesterol metaboli63%
related🧫Experiment: Multi-Ethnic PD GWAS63%
see_also📖Astrocytes60%
see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%
see_also📖ABCA7 (Redirect)60%
see_also📖Apoptosis in Neurodegeneration60%
see_also📖Amyloid-Related Imaging Abnormalities (ARIA)60%
see_also📖Autophagy Enhancement Drug Screening for Neurodegeneration60%
see_also📖ABCA1 - ATP-Binding Cassette Transporter A160%
see_also📖ASAH1 — N-Acylsphingosine Amidohydrolase 160%
see_also📖CTSF Gene (CLN10)60%
see_also📖IDUA Gene60%
see_also📖NPC2 — NPC Intracellular Cholesterol Transporter 260%
see_also📖hypotheses-apoe-contributes-alzheimers-disease-regulat60%
see_also📖APP Gene Dosage Reduction Therapy for Down Syndrome60%
see_also📖Alzheimer Indonesia60%
see_also📖C560%
see_also📖C5 Protein60%
see_also📖AQP4 (Aquaporin-4 Gene)60%
see_also📖EPHA8 Gene60%
mentions🔬What are the mechanisms underlying 4r-tau strain-specific sp50%
mentions🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas50%
mentions🧪Sphingomyelin Synthase Activators for Raft Remodeling50%
mentions🧫Experiment: Multi-Ethnic PD GWAS50%
mentions🧪Glymphatic System-Enhanced Antibody Clearance Reversal50%
mentions🧪SASP-Driven Aquaporin-4 Dysregulation50%
mentions🧪Complement C1q Mimetic Decoy Therapy50%
mentions🧪Purinergic P2Y12 Inverse Agonist Therapy50%
mentions🧪CYP46A1 Overexpression Gene Therapy50%
mentions🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas50%
related🔬What are the mechanisms underlying blood-brain barrier trans50%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪Netrin-1 Gradient Restoration40%
related🧪Ganglioside Rebalancing Therapy40%
related🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors40%
related🧪Complement C1q Subtype Switching40%
related🧪Microglial Purinergic Reprogramming40%
related🧪Sphingolipid Metabolism Reprogramming40%
related🧪Membrane Cholesterol Gradient Modulators40%
related🧪Flotillin-1 Stabilization Compounds40%
related🧪Glial Glycocalyx Remodeling Therapy40%
related🧪Aquaporin-4 Polarization Rescue40%
related🧪Ephrin-B2/EphB4 Axis Manipulation40%
related🧪Sphingomyelin Synthase Activators for Raft Remodeling40%
related🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia40%
related🧪GFAP-Positive Reactive Astrocyte Subtype Delineation40%
related🧪Complement C1QA Spatial Gradient in Cortical Layers40%
related🧪Excitatory Neuron Vulnerability via SLC17A7 Downregulation40%
related🧪APOE Isoform Expression Across Glial Subtypes40%
related🧪CYP46A1 Overexpression Gene Therapy40%
related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th40%
related🧪Sphingomyelin Synthase Activators for Raft Remodeling40%
related🧪Ganglioside Rebalancing Therapy40%
related🔬What are the mechanisms underlying 4r-tau strain-specific sp40%
related🔬PSP and CBD both involve 4R-tau but produce distinct neuropa40%
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