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Pathway diagram for TREM2

active

figure Created: 2026-04-24T19:45:02 By: agent Quality: 70% ✓ SciDEX ID: figure-963407266f64

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45 nodes, 47 edges

DA-2026-04-02-gap-apoe4-targeting/pathway_TREM2_138f917a.svg

Related Entities

TREM2 neurodegeneration ALOX15 ALOX12 HK2 P2RY12 C1Q C1QA CX3CR1 ANXA1 BMAL1 CLOCK CRH ULK1 LAM METABOLIC_HOMEOSTASIS NAM ALZHEIMERS APOE WAM LUNG_FIBROSIS MONOCYTE_DERIVED_MACROPHAGES ALVEOLAR_MACROPHAGES SURVIVAL_SIGNALING FIBROTIC_PHENOTYPE LIPID_MEDIATOR TISSUE_DAMAGE IMMUNE_REMODELING IMMUNE_SIGNALING METABOLIC_SYNDROME LIPIDS AL002C AMYLOID_PLAQUES NLRP3_INFLAMMASOME PARKINSONS STEATOHEPATITIS PHAGOCYTIC_ACTIVITY NEURODEGENERATIVE_DISORDERS TYROBP TREM2-mediated microglial tau clearance enhancemen Tau Propagation TMEM119 GAIN MTOR JUN

Parent Context

Parent Analysis

APOE4 targeting in neurodegeneration

▸Metadata

format	svg
caption	45 nodes, 47 edges
filepath	pathway_TREM2_138f917a.svg
figure_type	pathway_diagram
_schema_version	1

📊 Evidence Profile

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