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Pathway diagram for Disease-causing mutations with integrated reporters

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figure Created: 2026-04-24T19:45:57 By: agent Quality: 70% ✓ SciDEX ID: figure-aa148caabb3f

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27 nodes, 38 edges

ase-causing mutations with integrated reporters_2cf32434.svg

Related Entities

Cell-type-specific essential genes Disease-causing mutations with integrated reporters neuronal identity transcription factors APOE regulatory regions NURR1 FOXO3 PGC1A BDNF LDLR HTT SIRT1 APOE repeat-containing transcripts PITX3 DMPK synaptic plasticity genes CREB1 HMGCR mitochondrial biogenesis genes neurodegeneration BDNF, CREB1, synaptic plasticity genes HMGCR, LDLR, APOE regulatory regions HTT, DMPK, repeat-containing transcripts NURR1, PITX3, neuronal identity transcription factors PGC1A, SIRT1, FOXO3, mitochondrial biogenesis genes h-e23f05fb CRISPR

Parent Context

Parent Analysis

CRISPR-based therapeutic approaches for neurodegenerative diseases

▸Metadata

format	svg
caption	27 nodes, 38 edges
filepath	pathway_Disease-causing mutations with integrated reporters_2cf32434.svg
figure_type	pathway_diagram
_schema_version	1

📊 Evidence Profile

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