Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about anxa11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | ANXA11 |
| Chromosome | 10q22.3 |
| Function | N-terminal low-complexity domain (LCD, residues 1–188): An intrinsically disordered region enriched in glycine and proline residues. |
| Primary Expression | Motor neurons, Cortex, Hippocampus, Spinal cord |
| Amino Acids | 505 aa |
| UniProt ID | P50995 |
| Ensembl ID | ENSG00000122359 |
| OMIM | 602572 |
| GeneCards | ANXA11 |
| Human Protein Atlas | ANXA11 |
| KG Connections | 3 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
ANXA11["ANXA11"]
ANXA11 -->|"involved_in"| Amyloid_Filaments["Amyloid Filaments"]
ANXA11 -.biomarker for.-> FTLD_TDP_Type_C["FTLD-TDP Type C"]
ANXA11 -->|"binds"| miR_16_5p["miR-16-5p"]
ANXA11 -.biomarker for.-> bladder_cancer["bladder cancer"]
ANXA11 -->|"interacts"| TDP_43["TDP-43"]
ANXA11 -.biomarker for.-> IgG4_related_cholangitis["IgG4-related cholangitis"]
ANXA11 -->|"expressed in"| cholangiocyte["cholangiocyte"]
ANXA11 -->|"regulates"| calcium_homeostasis["calcium homeostasis"]
miR_16_5p -->|"regulates"| ANXA11
TARDBP["TARDBP"] -->|"interacts"| ANXA11Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||