CYLD

Understanding Entity Pages

This page aggregates everything SciDEX knows about CYLD: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CYLD is a gene implicated in neurodegeneration research. Key relationships include: activates, associated with, regulates. Associated with Als, Cancer, Infection. Connected to 53 entities in the SciDEX knowledge graph.

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graph TD
    CYLD["<b>CYLD</b>"]
    Inflammation{"Inflammation"}
    CYLD -->|"activates"| Inflammation
    Als{"Als"}
    CYLD -->|"associated with"| Als
    Cancer{"Cancer"}
    CYLD -->|"associated with"| Cancer
    Tumor{"Tumor"}
    CYLD -->|"associated with"| Tumor
    CYLD -->|"activates"| Als
    APAF1["APAF1"]
    CYLD -->|"activates"| APAF1
    TXNIP["TXNIP"]
    CYLD -->|"activates"| TXNIP
    TBK1["TBK1"]
    CYLD -->|"activates"| TBK1
    Er_Stress(["Er Stress"])
    CYLD -->|"activates"| Er_Stress
    CANCER["CANCER"]
    CYLD -->|"associated with"| CANCER
    ERK1["ERK1"]
    CYLD -->|"inhibits"| ERK1
    ERK2["ERK2"]
    CYLD -->|"associated with"| ERK2
    STING["STING"]
    STING -->|"activates"| CYLD
    GENES["GENES"]
    GENES -->|"activates"| CYLD
    NRF2["NRF2"]
    NRF2 -->|"activates"| CYLD
    ERK["ERK"]
    ERK -->|"regulates"| CYLD
    UBIQUITIN["UBIQUITIN"]
    UBIQUITIN -->|"regulates"| CYLD
    TLR4["TLR4"]
    TLR4 -->|"regulates"| CYLD
    CYTOKINES["CYTOKINES"]
    CYTOKINES -->|"activates"| CYLD
    style CYLD fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0