concept

B4GALT6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about B4GALT6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

46Connections

0Hypotheses

0Analyses

39Outgoing

7Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	B4GALT6
Key Genes/Proteins	LACCER
Related Diseases	Experimental Autoimmune Encephalomyelitis, Multiple Sclerosis, Neurodegeneration, Inflammation, Als

Wiki Pages (1)

Knowledge base pages for this entity

Gangliosides in Neurodegeneration

mechanism · 3136 words

→

Pathway Diagram

graph TD
    B4GALT6["B4GALT6"]
    B4GALT6 -->|"catalyzes"| LacCer["LacCer"]
    B4GALT6 -->|"catalyzes"| Lactosylceramide["Lactosylceramide"]
    B4GALT6 -->|"regulates"| Astrocyte_Activation["Astrocyte Activation"]
    B4GALT6 -->|"regulates"| Chronic_CNS_Inflammation["Chronic CNS Inflammation"]
    B4GALT6 -->|"regulates"| Central_Nervous_System_Innate_["Central Nervous System Innate Immunity"]
    B4GALT6 -->|"upregulates"| Experimental_Autoimmune_Enceph["Experimental Autoimmune Encephalomyelitis"]
    B4GALT6 -->|"encodes"| LACCER["LACCER"]
    B4GALT6 -->|"activates"| Neurodegeneration["Neurodegeneration"]
    ASTROCYTES["ASTROCYTES"] -->|"activates"| B4GALT6
    CCL2["CCL2"] -->|"activates"| B4GALT6
    MICROGLIA["MICROGLIA"] -->|"activates"| B4GALT6
    ASTROCYTE["ASTROCYTE"] -->|"activates"| B4GALT6
    INFLAMMATION["INFLAMMATION"] -->|"activates"| B4GALT6
    NEURODEGENERATION["NEURODEGENERATION"] -->|"activates"| B4GALT6

Outgoing (39)

Target	Relation	Type	Str
Lactosylceramide	associated_with	compound	0.95
Lactosylceramide	catalyzes	compound	0.95
Experimental Autoimmune Encephalomyelitis	associated_with	disease	0.90
Astrocyte Activation	regulates	process	0.90
LACCER	synthesizes	compound	0.90
Multiple Sclerosis	associated_with	disease	0.85
Central Nervous System Innate Immunity	regulates	process	0.85
LACCER	encodes	protein	0.72
Neurodegeneration	activates	disease	0.65
Multiple Sclerosis	activates	disease	0.65
Inflammation	activates	disease	0.65
Als	expressed_in	disease	0.65
Autoimmune	activates	disease	0.65
Ms	activates	disease	0.65
ALS	expressed_in	disease	0.65
MS	associated_with	disease	0.64
Innate Immunity	activates	pathway	0.60
ASTROCYTES	activates	gene	0.60
MICROGLIA	activates	gene	0.60
CCL2	activates	gene	0.60
INFLAMMATION	activates	gene	0.60
NEURODEGENERATION	activates	gene	0.60
ASTROCYTE	activates	gene	0.60
Neuroinflammatory	activates	pathway	0.60
ASTROCYTE	therapeutic_target	gene	0.60
AND	expressed_in	gene	0.60
Macrophage	activates	cell_type	0.60
Monocyte	activates	cell_type	0.60
Microglia	activates	cell_type	0.60
Astrocyte	therapeutic_target	cell_type	0.60
Chemokine	activates	protein	0.60
Ras	activates	protein	0.60
multiple sclerosis	activates	disease	0.60
oxidative stress response	participates_in	pathway	0.60
neuroinflammation	activates	disease	0.60
astrocytes	expressed_in	cell_type	0.60
Macrophage	expressed_in	cell_type	0.55
Astrocyte	expressed_in	cell_type	0.55
Microglia	expressed_in	cell_type	0.55

Incoming (7)

Source	Relation	Type	Str
ASTROCYTES	activates	gene	0.60
CCL2	activates	gene	0.60
MICROGLIA	activates	gene	0.60
ASTROCYTE	activates	gene	0.60
INFLAMMATION	activates	gene	0.60
NEURODEGENERATION	activates	gene	0.60
ASTROCYTE	therapeutic_target	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found