gene

CNBP

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CNBP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

39Connections
0Hypotheses
0Analyses
26Outgoing
13Incoming

Summary

Comprehensive review of CNBP gene, a zinc-finger protein implicated in Myotonic Dystrophy Type 2 and neurodegenerative disease pathogenesis

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🧬 Gene Info
Gene SymbolCNBP
Full NameCellular Nucleic Acid Binding Protein
Chromosome3q21.3
Protein FamilyCCHC-type zinc finger
Functionis a human gene located on chromosome 3q21.
Primary ExpressionSkeletal muscle, Heart, Brain, Spinal cord
Amino Acids182 aa
UniProt IDQ9GZL0
NCBI Gene ID28985
Ensembl IDENSG00000182021
OMIM116955
GeneCardsCNBP
Human Protein AtlasCNBP
AliasZNF9, ZNF7
Protein Length182 amino acids
Associated DiseasesALS, Amyotrophic Lateral Sclerosis, Myotonic Dystrophy Type 2, Neurodegeneration, Parkinson's disease, Tauopathy
KG Connections39 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: CNBP — AlphaFold Q9GZL0 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (8)

Knowledge base pages for this entity

Canonical Page

CNBP — Cellular Nucleic Acid Binding Protein

gene · 2009 words

Trinucleotide Repeat Expansion Disorders

mechanism · 3379 words

RAN Translation in Neurodegeneration

mechanism · 2989 words

mbnl1

gene · 2787 words

Myotonic Dystrophy

disease · 2283 words

Muscular Dystrophy

disease · 1399 words

Pathway Diagram

graph TD
    CNBP["<b>CNBP</b>"]
    Als{"Als"}
    CNBP -->|"therapeutic target"| Als
    Ms{"Ms"}
    CNBP -->|"therapeutic target"| Ms
    MTDNA["MTDNA"]
    CNBP -->|"therapeutic target"| MTDNA
    Autophagy(["Autophagy"])
    CNBP -->|"therapeutic target"| Autophagy
    Mitophagy(["Mitophagy"])
    CNBP -->|"therapeutic target"| Mitophagy
    neurodegeneration["neurodegeneration"]
    CNBP -->|"implicated in"| neurodegeneration
    BNIP3["BNIP3"]
    BNIP3 -->|"therapeutic target"| CNBP
    MITOPHAGY["MITOPHAGY"]
    MITOPHAGY -->|"therapeutic target"| CNBP
    P62["P62"]
    P62 -->|"therapeutic target"| CNBP
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"]
    MITOCHONDRIAL_DNA -->|"therapeutic target"| CNBP
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"]
    MITOCHONDRIAL_DYSFUNCTION -->|"therapeutic target"| CNBP
    AUTOPHAGY["AUTOPHAGY"]
    AUTOPHAGY -->|"therapeutic target"| CNBP
    style CNBP fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (26)

TargetRelationTypeStr
Myotonic Dystrophy Type 2causesdisease0.95
Alstherapeutic_targetdisease0.65
Mstherapeutic_targetdisease0.65
Neurodegenerationassociated_withdisease0.65
Amyotrophic Lateral Sclerosisassociated_withdisease0.65

Incoming (13)

SourceRelationTypeStr
BNIP3therapeutic_targetgene0.60
P62therapeutic_targetgene0.60
MITOPHAGYtherapeutic_targetgene0.60
MITOCHONDRIAL DNAtherapeutic_targetgene0.60
MITOCHONDRIAL DYSFUNCTIONtherapeutic_targetgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found