gene

KIF15

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KIF15: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

42Connections

0Hypotheses

0Analyses

25Outgoing

17Incoming

0Experiments

Summary

Page for KIF15 Gene - Kinesin Family Member 15

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🧬 Gene Info

Gene Symbol	KIF15
Full Name	Kinesin Family Member 15
Aliases	Page for KIF15 Gene
Chromosome	3p21.31
Function	Mitotic spindle assembly, chromosome segregation
Primary Expression	Cerebral cortex, Hippocampus, Testis, Proliferating cells
Molecular Weight	200 kDa
Amino Acids	1798 aa
Pathways	Pyroptosis
UniProt ID	Q9Y5D2
NCBI Gene ID	56992
Ensembl ID	ENSG00000163808
GeneCards	KIF15
Human Protein Atlas	KIF15
Associated Diseases	Parkinson's Disease
Interactions	KIF5B, PVALB, RANK, STING, CGAS, PYROPTOSIS
KG Connections	42 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KIF15 — AlphaFold Q9Y5D2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KIF15 Gene - Kinesin Family Member 15

gene · 766 words

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Genes

index · 271 words

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Pathway Diagram

graph TD
    KIF15["<b>KIF15</b>"]
    Cancer{"Cancer"}
    KIF15 -->|"activates"| Cancer
    Tumor{"Tumor"}
    KIF15 -->|"activates"| Tumor
    Pyroptosis(["Pyroptosis"])
    KIF15 -->|"activates"| Pyroptosis
    neurodegeneration["neurodegeneration"]
    KIF15 -->|"implicated in"| neurodegeneration
    PYROPTOSIS["PYROPTOSIS"]
    PYROPTOSIS -->|"activates"| KIF15
    CANCER["CANCER"]
    CANCER -->|"activates"| KIF15
    CGAS_STING["CGAS-STING"]
    CGAS_STING -->|"activates"| KIF15
    STING["STING"]
    STING -->|"activates"| KIF15
    CGAS["CGAS"]
    CGAS -->|"activates"| KIF15
    style KIF15 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (25)

Target	Relation	Type	Str
Cancer	activates	disease	0.65
Tumor	activates	disease	0.65
NEFL	associated_with	gene	0.60
AURKB	associated_with	gene	0.60
TPR	associated_with	gene	0.60
RANK	therapeutic_target	gene	0.60
CALM1	associated_with	gene	0.60
NEFH	associated_with	gene	0.60
KIF5B	associated_with	gene	0.60
CDC42	associated_with	gene	0.60
PVALB	associated_with	gene	0.60
SST	associated_with	gene	0.60
GAP43	associated_with	gene	0.60
RANK	interacts_with	gene	0.60
MKI67	associated_with	gene	0.60
Pyroptosis	activates	pathway	0.60
AND	associated_with	gene	0.60
HUB GENES	associated_with	gene	0.60
KIF5B	interacts_with	gene	0.50
NEFH	co_discussed	gene	0.50
NEFL	co_discussed	gene	0.50
PVALB	interacts_with	gene	0.50
KIF5B	co_expressed_with	gene	0.50
NEFH	co_expressed_with	gene	0.50
ASPM	associated_with	protein	0.50

Incoming (17)

Source	Relation	Type	Str
STING	activates	gene	0.60
CGAS	activates	gene	0.60
TPR	associated_with	gene	0.60
CDC42	associated_with	gene	0.60
NEFL	associated_with	gene	0.60
GAP43	associated_with	gene	0.60
CALM1	associated_with	gene	0.60
KIF5B	associated_with	gene	0.60
AURKB	associated_with	gene	0.60
PYROPTOSIS	activates	gene	0.60
CANCER	activates	gene	0.60
CGAS-STING	activates	gene	0.60
GENES	associated_with	gene	0.60
RANK	regulates	gene	0.50
CDC42	co_expressed_with	gene	0.50
GAP43	co_expressed_with	protein	0.50
GENES	regulates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found