NEFL

Understanding Entity Pages

This page aggregates everything SciDEX knows about NEFL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

NEFL is a gene implicated in neurodegeneration research. Key relationships include: biomarker for, associated with, interacts with. Associated with ALS, ALZHEIMER'S DISEASE, Als. Connected to 88 entities in the SciDEX knowledge graph.

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flowchart TD
    TPM2["TPM2"] -->|"binds"| NEFL["NEFL"]
    NEFL["NEFL"] -->|"biomarker for"| Neurodegeneration["Neurodegeneration"]
    NEFL["NEFL"] -->|"biomarker for"| Als["Als"]
    NEFL["NEFL"] -->|"biomarker for"| Inflammation["Inflammation"]
    NEFL["NEFL"] -->|"biomarker for"| Neuroinflammation["Neuroinflammation"]
    NEFL["NEFL"] -->|"biomarker for"| Alzheimer["Alzheimer"]
    NEFL["NEFL"] -->|"therapeutic target"| Alzheimer["Alzheimer"]
    NEFL["NEFL"] -->|"therapeutic target"| Als["Als"]
    NEFL["NEFL"] -->|"interacts with"| Als["Als"]
    NEFL["NEFL"] -->|"interacts with"| Ms["Ms"]
    NEFL["NEFL"] -->|"interacts with"| Amyotrophic_Lateral_Scler["Amyotrophic Lateral Sclerosis"]
    NEFL["NEFL"] -->|"biomarker for"| ALS["ALS"]
    style TPM2 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style NEFL fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style Neurodegeneration fill:#ef5350,stroke:#333,color:#e0e0e0
    style Als fill:#ef5350,stroke:#333,color:#e0e0e0
    style Inflammation fill:#ef5350,stroke:#333,color:#e0e0e0
    style Neuroinflammation fill:#ef5350,stroke:#333,color:#e0e0e0
    style Alzheimer fill:#ef5350,stroke:#333,color:#e0e0e0
    style Ms fill:#ef5350,stroke:#333,color:#e0e0e0
    style Amyotrophic_Lateral_Scler fill:#ef5350,stroke:#333,color:#e0e0e0
    style ALS fill:#ef5350,stroke:#333,color:#e0e0e0