concept

MURF1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MURF1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

34Connections
0Hypotheses
0Analyses
20Outgoing
14Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameMURF1
Key Genes/ProteinsP16, P53, P21, AGING
Related DiseasesMs, Als, Aging, ALS
Related PathwaysAkt, Pi3K, Oxidative Stress, Mitochondrial Function, Mtor

Wiki Pages (2)

Knowledge base pages for this entity

TRIM63 Gene

gene · 987 words

Skeletal Muscle Cells

cell · 686 words

Pathway Diagram

graph TD
    MURF1["MURF1"]
    MURF1 -->|"contributes to"| Skeletal_Muscle_Aging["Skeletal Muscle Aging"]
    MURF1 -->|"activates"| Ms["Ms"]
    MURF1 -->|"activates"| Als["Als"]
    MURF1 -->|"activates"| Aging["Aging"]
    MURF1 -->|"activates"| ALS["ALS"]
    MURF1 -->|"activates"| Akt["Akt"]
    MURF1 -->|"activates"| Pi3K["Pi3K"]
    MURF1 -->|"activates"| Oxidative_Stress["Oxidative Stress"]
    OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"activates"| MURF1
    AGING["AGING"] -->|"activates"| MURF1
    AKT["AKT"] -->|"activates"| MURF1
    P21["P21"] -->|"regulates"| MURF1
    P53["P53"] -->|"regulates"| MURF1
    PI3K["PI3K"] -->|"activates"| MURF1
    P16["P16"] -->|"regulates"| MURF1
    PSP["PSP"] -->|"regulates"| MURF1

Outgoing (20)

TargetRelationTypeStr
Skeletal Muscle Agingcontributes_toprocess0.80
Skeletal Muscle Agingassociated_withprocess0.75
Msactivatesdisease0.65
Alsactivatesdisease0.65
Agingactivatesdisease0.65

Incoming (14)

SourceRelationTypeStr
OXIDATIVE STRESSactivatesgene0.60
AGINGactivatesgene0.60
AKTactivatesgene0.60
P21regulatesgene0.60
P53regulatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found