RPS6KA1

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPS6KA1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

RPS6KA1 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, associated with, implicated in. Associated with Als, Cancer, Carcinoma. Connected to 28 entities in the SciDEX knowledge graph.

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graph TD
    RPS6KA1["<b>RPS6KA1</b>"]
    Inflammation{"Inflammation"}
    RPS6KA1 -->|"therapeutic target"| Inflammation
    Als{"Als"}
    RPS6KA1 -->|"therapeutic target"| Als
    RPS6KA1 -->|"associated with"| Als
    Cancer{"Cancer"}
    RPS6KA1 -->|"associated with"| Cancer
    Carcinoma{"Carcinoma"}
    RPS6KA1 -->|"associated with"| Carcinoma
    HIF1A["HIF1A"]
    RPS6KA1 -->|"therapeutic target"| HIF1A
    GRIN1["GRIN1"]
    RPS6KA1 -->|"therapeutic target"| GRIN1
    ADAM10["ADAM10"]
    RPS6KA1 -->|"therapeutic target"| ADAM10
    Oxidative_Stress(["Oxidative Stress"])
    RPS6KA1 -->|"therapeutic target"| Oxidative_Stress
    Nf__b(["Nf-Kappab"])
    RPS6KA1 -->|"therapeutic target"| Nf__b
    Apoptosis(["Apoptosis"])
    RPS6KA1 -->|"therapeutic target"| Apoptosis
    TRIM37["TRIM37"]
    RPS6KA1 -->|"associated with"| TRIM37
    GENES["GENES"]
    GENES -->|"therapeutic target"| RPS6KA1
    CAPN1["CAPN1"]
    CAPN1 -->|"therapeutic target"| RPS6KA1
    TTR["TTR"]
    TTR -->|"therapeutic target"| RPS6KA1
    LGALS3["LGALS3"]
    LGALS3 -->|"therapeutic target"| RPS6KA1
    CTSD["CTSD"]
    CTSD -->|"therapeutic target"| RPS6KA1
    GRB2["GRB2"]
    GRB2 -->|"therapeutic target"| RPS6KA1
    TLR4["TLR4"]
    TLR4 -->|"therapeutic target"| RPS6KA1
    NFE2L2["NFE2L2"]
    NFE2L2 -->|"therapeutic target"| RPS6KA1
    NFKB1["NFKB1"]
    NFKB1 -->|"associated with"| RPS6KA1
    RAB7A["RAB7A"]
    RAB7A -->|"associated with"| RPS6KA1
    CTNNB1["CTNNB1"]
    CTNNB1 -->|"associated with"| RPS6KA1
    KNL1["KNL1"]
    KNL1 -->|"associated with"| RPS6KA1
    style RPS6KA1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0