Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC3A2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SLC3A2 |
| Key Genes/Proteins | TMEM16F, LAMP1, CD63, CD9, EXOSOMES, ENDOSOMES |
| Related Diseases | Carcinoma, Cancer |
| Related Pathways | Tgf-Β, Mtor |
Knowledge base pages for this entity
graph TD
SLC3A2["SLC3A2"]
SLC3A2 -.biomarker for.-> Carcinoma["Carcinoma"]
SLC3A2 -.biomarker for.-> Cancer["Cancer"]
SLC3A2 -->|"interacts"| CD63["CD63"]
SLC3A2 -->|"interacts"| CD9["CD9"]
SLC3A2 -->|"interacts"| ENDOSOMES["ENDOSOMES"]
SLC3A2 -.biomarker for.-> CANCER["CANCER"]
SLC3A2 -->|"regulates"| HSPA1A["HSPA1A"]
SLC3A2 -->|"regulates"| CTSS["CTSS"]
TMEM16F["TMEM16F"] -->|"regulates"| SLC3A2
PI3K["PI3K"] -.biomarker for.-> SLC3A2
AND["AND"] -->|"regulates"| SLC3A2| Target | Relation | Type | Str |
|---|---|---|---|
| Carcinoma | biomarker_for | disease | 0.65 |
| Cancer | biomarker_for | disease | 0.65 |
| LAMP1 | associated_with | gene | 0.60 |
| CD63 | interacts_with | gene | 0.60 |
| CD9 | interacts_with | gene | 0.60 |
| EXOSOMES | associated_with | gene | 0.60 |
| ENDOSOMES | interacts_with | gene | 0.60 |
| CANCER | biomarker_for | gene | 0.60 |
| HSPA1A | regulates | gene | 0.60 |
| CTSS | regulates | gene | 0.60 |
| AKT | biomarker_for | gene | 0.60 |
| MTOR | biomarker_for | gene | 0.60 |
| Tgf-Β | biomarker_for | pathway | 0.60 |
| Mtor | biomarker_for | pathway | 0.60 |
| Akt | biomarker_for | pathway | 0.60 |
| Pi3K | biomarker_for | pathway | 0.60 |
| SLC7A11 | inhibits | gene | 0.55 |
| autophagy pathway | participates_in | pathway | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||