gene 1,725 words KG: ent-gene-6a3429a9
Contents

ACTB Gene

🧬 Gene Info
Gene SymbolACTB
Full NameBeta-Actin
Chromosome7p22.1
Functionis a globular protein with a molecular weight of approximately 42 kDa.
Molecular Weight42 kDa
Exons6
PathwaysAutophagy, Chaperone, Mapk, Mtor, Oxidative Stress
UniProt IDP60709
NCBI Gene ID81
Ensembl IDENSG00000075624
OMIM102630
GeneCardsACTB
Human Protein AtlasACTB
Associated DiseasesAD, ADH, ALI, Als, Alzheimer, AMI
Known Drugs/Compoundsrapamycin, statins
Interactions4E-BP1, ABCA1, ABCG1, ACTG1, Actin, AGING
KG Connections1090 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (38)

Lysosomal Positioning Dynamics Modulation
Score: 0.69
R-Loop Resolution Enhancement Therapy
Score: 0.68
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
RNA Granule Nucleation Site Modulation
Score: 0.66
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.57
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.57
Piezoelectric Nanochannel BBB Disruption
Score: 0.52
APOE-Dependent Autophagy Restoration
Score: 0.89
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
APOE Isoform Conversion Therapy
Score: 0.72
Astrocytic Connexin-43 Upregulation Enhances Neuroprotective
Score: 0.68
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65
TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62
Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
← Prevpg 2/2

Related Analyses (9)

Gene expression changes in aging mouse brain predicting neur
neurodegeneration · completed
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (8)

ABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: activates
ABCG1 Gene
gene · KG edge: interacts_with
ACTG1 Gene
gene · KG edge: associated_with
AIF1 Gene
gene · KG edge: associated_with
AKT1 Gene
gene · KG edge: interacts_with

Knowledge Graph (2 edges)

ent-gene-6a3429a9 data_in benchmark_ot_ad_answer_key:ACTB
benchmark_ot_ad_answer_key:ACTB data_in ent-gene-6a3429a9

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