| Gene Symbol | PDK1 |
| Function | Recent advances in proteomics have revealed remarkable convergence in protein alterations across distinct neurodegenerative diseases |
| Pathways | Cell Cycle, Differentiation, Glycolysis, Mitosis, Pi3K/Akt |
| GeneCards | PDK1 |
| Human Protein Atlas | PDK1 |
| Protein | AD Change |
| IL-6 | ↑ |
| TNF-α | ↑ |
| C3 | ↑ |
| TREM2 | ↑ (variants) |
| APOE | ε4: ↑ |
| Associated Diseases | Aging, Als, Carcinoma, Cirrhosis, Infection, Ms |
| Interactions | MTOR, EGFR, ERCC3, CEBPB, EGF, PI3K |
| KG Connections | 180 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |