gene 1,654 words KG: PECAM1
Contents

PECAM1 - Platelet Endothelial Cell Adhesion Molecule 1

🧬 Gene Info
Gene SymbolPECAM1
Full NamePlatelet Endothelial Cell Adhesion Molecule 1
Chromosome17q23
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight72 kDa
Amino Acids738 aa
UniProt IDP16284
NCBI Gene ID5175
Ensembl IDENSG00000261371
GeneCardsPECAM1
Human Protein AtlasPECAM1
Associated DiseasesAls, Atherosclerosis, Cancer, Coronary Artery Disease, Inflammation, Myocardial Infarction
InteractionsCD36, CD38, CD4, IL1A, MS4A6A, PTGER2
SciDEX HypothesesCirculating Endothelial Microparticles Expressing
KG Connections73 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (6)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

Genes
index · KG edge: associated_with
CAV1
gene · KG edge: associated_with
CD14 — CD14 Molecule
gene · KG edge: associated_with
DNAJB9 Gene
gene · KG edge: protects_against
ERN1 — Endoplasmic Reticulum To Nucleus Signaling 1
gene · KG edge: protects_against

Knowledge Graph (12 edges)

PECAM1 protects_against FOS
PECAM1 protects_against FGF1
PECAM1 protects_against FGF5
PECAM1 interacts_with IL1A
PECAM1 protects_against XBP1
PECAM1 protects_against DNAJB9
PECAM1 protects_against ERN1
PECAM1 protects_against PDIA6
PECAM1 associated_with IL6
PECAM1 associated_with MMP9

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