MS4A6A

Understanding Entity Pages

This page aggregates everything SciDEX knows about MS4A6A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Membrane Spanning 4-Domains A6A, Alzheimer's disease risk gene involved in microglial signaling

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graph TD
    MS4A6A["<b>MS4A6A</b>"]
    OPTN["OPTN"]
    MS4A6A -->|"associated with"| OPTN
    PARK7["PARK7"]
    MS4A6A -->|"associated with"| PARK7
    PARKINSON["PARKINSON"]
    MS4A6A -->|"associated with"| PARKINSON
    PINK1["PINK1"]
    MS4A6A -->|"associated with"| PINK1
    PSEN1["PSEN1"]
    MS4A6A -->|"associated with"| PSEN1
    PSEN2["PSEN2"]
    MS4A6A -->|"associated with"| PSEN2
    SNCA["SNCA"]
    MS4A6A -->|"associated with"| SNCA
    SOD1["SOD1"]
    MS4A6A -->|"associated with"| SOD1
    TAU["TAU"]
    MS4A6A -->|"associated with"| TAU
    TBK1["TBK1"]
    MS4A6A -->|"associated with"| TBK1
    TREM2["TREM2"]
    MS4A6A -->|"associated with"| TREM2
    VPS35["VPS35"]
    MS4A6A -->|"associated with"| VPS35
    ABCA7["ABCA7"]
    ABCA7 -->|"associated with"| MS4A6A
    ALPHA_SYNUCLEIN["ALPHA-SYNUCLEIN"]
    ALPHA_SYNUCLEIN -->|"associated with"| MS4A6A
    ALS["ALS"]
    ALS -->|"associated with"| MS4A6A
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"associated with"| MS4A6A
    AMYLOID["AMYLOID"]
    AMYLOID -->|"associated with"| MS4A6A
    APOE["APOE"]
    APOE -->|"associated with"| MS4A6A
    APP["APP"]
    APP -->|"associated with"| MS4A6A
    ATP13A2["ATP13A2"]
    ATP13A2 -->|"associated with"| MS4A6A
    AUTOPHAGY["AUTOPHAGY"]
    AUTOPHAGY -->|"associated with"| MS4A6A
    BIN1["BIN1"]
    BIN1 -->|"associated with"| MS4A6A
    C9ORF72["C9ORF72"]
    C9ORF72 -->|"associated with"| MS4A6A
    CD33["CD33"]
    CD33 -->|"associated with"| MS4A6A
    style MS4A6A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0