gene 717 words KG: RANKINGS 2026-03-24
kind:genesection:genesstate:published
Contents

Gene Rankings

🧬 Gene Info
Gene Symbolrankings
PathwaysInsulin Signaling, Akt, Mapk, Pi3K
RankGene
1C9orf72
2SOD1
3TARDBP (TDP-43)
4PARK2 (Parkin)
5PINK1
6DJ-1
7VPS35
8DNAJC13
9UCHL1
10GIGYF2
Associated DiseasesLymphoma
InteractionsRAC1, PI3K, AKT, RHOA, TRAF2, TRAF6
KG Connections25 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (21)

TREM2-Dependent Microglial Senescence Transition
Score: 0.69
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Prodromal Parkinson's Disease Biomarker Development — Early
clinical · proposed · Score: 0.40

See Also (14)

MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: associated_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: interacts_with
Packard Center for ALS Research
institution · KG edge: interacts_with
TGFBR1 — TGF-beta Receptor 1
gene · KG edge: interacts_with
RHOA Gene — Ras Homolog Family Member A
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

RANKINGS interacts_with RAC1
RANKINGS associated_with MAPK1
RANKINGS interacts_with PI3K
RANKINGS associated_with CBL
RANKINGS interacts_with AKT
RANKINGS interacts_with RHOA
RANKINGS interacts_with TRAF2
RANKINGS interacts_with TRAF6
RANKINGS interacts_with TGFBR1
RANKINGS associated_with PTEN