gene 1,166 words KG: TAAR1 2026-03-25
kind:genesection:genestopic:alzheimerstopic:parkinsonstopic:psychiatry
Contents

TAAR1 — Trace Amine-Associated Receptor 1

🧬 Gene Info
Gene SymbolTAAR1
Full NameTAAR1 — Trace Amine-Associated Receptor 1
Chromosome12
Protein TypeGene
Functionis a G-protein-coupled receptor (GPCR) that responds to endogenous trace amines, including tyramine, β-phenylethylamine (PEA), and tryptamine[@gainetdinov2004].
Primary Expressionboth neurons and glial cells
Amino Acids339 aa
PathwaysMitochondrial Function
NCBI Gene IDSearch NCBI
GeneCardsTAAR1
Human Protein AtlasTAAR1
Associated DiseasesALS, Cardiomyopathy, Inflammation, Lymphoma, Ms, Retinopathy
Known Drugs/Compoundsrapamycin
InteractionsAADC, SIGMAR1, MYD88, CHOP, BCL2, NRF2
KG Connections160 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (4)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Smartphone-Detected Motor Variability Correction
Score: 0.56
Senescence-Associated Myelin Lipid Remodeling
Score: 0.51
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47

Related Analyses (7)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
TREM2 agonism vs antagonism in DAM microglia
neurodegeneration · failed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

CREB-independent Neuronal Survival Pathways
mechanism · KG edge: activates
Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: activates
chop
gene · KG edge: activates
BECN1 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

TAAR1 activates TRAF6
TAAR1 activates VEGF
TAAR1 associated_with SIGMAR1
TAAR1 associated_with MYD88
TAAR1 associated_with PUMA
TAAR1 associated_with TRAF6
TAAR1 associated_with FIS1
TAAR1 associated_with BAX
TAAR1 associated_with CHOP
TAAR1 associated_with VEGF