concept

IL13RA1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL13RA1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

59Connections

0Hypotheses

0Analyses

38Outgoing

21Incoming

0Experiments

No summary available yet. View on Wiki →

💡 Concept Info

Name	IL13RA1
Key Genes/Proteins	LDLR, MSR1, GENES, NTS
Related Diseases	Coronary Artery Disease, Atherosclerosis, ATHEROSCLEROSIS, Fibrosis, Als

Pathway Diagram

graph TD
    IL13RA1["IL13RA1"]
    IL13RA1 -.biomarker for.-> Coronary_Artery_Disease["Coronary Artery Disease"]
    IL13RA1 -->|"binds_to"| CAR_T_cells["CAR T cells"]
    IL13RA1 -->|"involved_in"| Atherosclerosis["Atherosclerosis"]
    IL13RA1 -->|"correlates_with"| LDLR["LDLR"]
    IL13RA1 -->|"contributes to"| ATHEROSCLEROSIS["ATHEROSCLEROSIS"]
    IL13RA1 -->|"regulates"| Fibrosis["Fibrosis"]
    IL13RA1 -.biomarker for.-> Als["Als"]
    IL1A["IL1A"] -.biomarker for.-> IL13RA1
    HTR3C["HTR3C"] -.biomarker for.-> IL13RA1
    CSF2["CSF2"] -.biomarker for.-> IL13RA1
    CXCL2["CXCL2"] -.biomarker for.-> IL13RA1
    NR4A2["NR4A2"] -.biomarker for.-> IL13RA1
    JAK1["JAK1"] -->|"regulates"| IL13RA1
    GENES["GENES"] -->|"regulates"| IL13RA1
    MMP9["MMP9"] -.biomarker for.-> IL13RA1

Outgoing (38)

Target	Relation	Type	Str
Coronary Artery Disease	biomarker_for	disease	0.95
CAR T cells	binds_to	cell_type	0.95
Atherosclerosis	involved_in	disease	0.85
LDLR	correlates_with	gene	0.80
ATHEROSCLEROSIS	contributes_to	disease	0.68
Fibrosis	regulates	disease	0.65
Als	biomarker_for	disease	0.65
Atherosclerosis	regulates	disease	0.65
Inflammation	regulates	disease	0.65
Ms	biomarker_for	disease	0.65
ALS	biomarker_for	disease	0.65
CORONARY_ARTERY_DISEASE	associated_with	disease	0.64
MSR1	biomarker_for	gene	0.60
GENES	regulates	gene	0.60
NTS	biomarker_for	gene	0.60
LDLR	associated_with	gene	0.60
NR4A2	biomarker_for	gene	0.60
CXCL2	biomarker_for	gene	0.60
JAK1	regulates	gene	0.60
CSF2	biomarker_for	gene	0.60
MMP9	biomarker_for	gene	0.60
STAT3	regulates	gene	0.60
Cholesterol	regulates	pathway	0.60
Immune Response	biomarker_for	pathway	0.60
HTR3C	biomarker_for	gene	0.60
RNA	biomarker_for	gene	0.60
AND	biomarker_for	gene	0.60
IL1A	biomarker_for	gene	0.60
CCR9	biomarker_for	gene	0.60
TNFRSF19	biomarker_for	gene	0.60
App	biomarker_for	protein	0.60
oxidative stress response	participates_in	pathway	0.60
LDLR	co_expressed_with	gene	0.60
NTS	co_expressed_with	gene	0.60
JAK-STAT signaling	participates_in	pathway	0.60
NTS	associated_with	gene	0.60
cardiovascular disease	associated_with	disease	0.60
cardiovascular disease	regulates	disease	0.60

Incoming (21)

Source	Relation	Type	Str
IL1A	biomarker_for	gene	0.60
HTR3C	biomarker_for	gene	0.60
CSF2	biomarker_for	gene	0.60
CXCL2	biomarker_for	gene	0.60
NR4A2	biomarker_for	gene	0.60
LDLR	associated_with	gene	0.60
JAK1	regulates	gene	0.60
GENES	regulates	gene	0.60
MMP9	biomarker_for	gene	0.60
NTS	biomarker_for	gene	0.60
INFLAMMATION	regulates	gene	0.60
STAT3	regulates	gene	0.60
MSR1	biomarker_for	gene	0.60
TNFRSF19	biomarker_for	gene	0.60
CCR9	biomarker_for	gene	0.60
RNA	biomarker_for	gene	0.60
AND	biomarker_for	gene	0.60
CCR9	co_expressed_with	gene	0.60
CSF2	co_expressed_with	gene	0.60
CCR9	associated_with	gene	0.60
CSF2	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found