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mechanism 1,197 words KG: MAPK/ERK
Contents

MAPK/ERK and JAK-STAT Signaling in 4R-Tauopathies

⚙ Mechanism Info
NameMAPK/ERK
Key Genes/ProteinsAKT, BDNF, EGR1, ERBB2, ERK, integrins
Related Pathwaysautophagy, PI3K/AKT

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Related Experiments (8)

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See Also (15)

erk-mapk-signaling-neurodegeneration
mechanism · KG edge: activatesPI3K — Phosphoinositide 3-Kinase
gene · KG edge: inhibitsAutophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activatesTARDBP — TAR DNA Binding Protein 43
gene · KG edge: phosphorylatesRas-MAPK Signaling Pathway in Neurodegeneration
mechanism · KG edge: inhibits

Knowledge Graph (12 edges)

autophagy activates MAPK/ERK
MAPK/ERK activates EGR1
SQSTM1/p62 inhibits MAPK/ERK
MAPK/ERK promotes neurodegeneration
integrins activates MAPK/ERK
reduced loading inhibits MAPK/ERK
ERK activates MAPK/ERK
MAPK activates MAPK/ERK
AUTOPHAGY activates MAPK/ERK
AKT inhibits MAPK/ERK

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