concept

MT-CO2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MT-CO2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

47Connections

0Hypotheses

0Analyses

28Outgoing

19Incoming

0Experiments

0Debates

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Pathway Diagram

graph TD
    MT_CO2["MT-CO2"]
    MT_CO2 -->|"regulates"| Alzheimer["Alzheimer"]
    MT_CO2 -->|"regulates"| Ms["Ms"]
    MT_CO2 -->|"regulates"| MT_ND4L["MT-ND4L"]
    MT_CO2 -->|"regulates"| APOPTOSIS["APOPTOSIS"]
    MT_CO2 -->|"regulates"| OXIDATIVE_STRESS["OXIDATIVE STRESS"]
    MT_CO2 -->|"regulates"| MST1["MST1"]
    MT_CO2 -->|"regulates"| Akt["Akt"]
    MT_CO2 -->|"regulates"| Mitochondrial_Function["Mitochondrial Function"]
    PGC1_["PGC1alpha"] -->|"regulates"| MT_CO2
    MT_ATP6["MT-ATP6"] -->|"regulates"| MT_CO2
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"regulates"| MT_CO2
    PI3K["PI3K"] -->|"regulates"| MT_CO2
    HIPPO["HIPPO"] -->|"regulates"| MT_CO2
    AKT["AKT"] -->|"regulates"| MT_CO2
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"] -->|"regulates"| MT_CO2
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"] -->|"regulates"| MT_CO2

Outgoing (28)

Target	Relation	Type	Str
Alzheimer	regulates	disease	0.65
Ms	regulates	disease	0.65
OXIDATIVE STRESS	regulates	gene	0.60
MST1	regulates	gene	0.60
Akt	regulates	pathway	0.60
Mitochondrial Function	regulates	pathway	0.60
Apoptosis	regulates	pathway	0.60
Immune Response	regulates	pathway	0.60
Oxidative Stress	regulates	pathway	0.60
MT-ND4L	regulates	gene	0.60
Pi3K	regulates	pathway	0.60
APOPTOSIS	regulates	gene	0.60
Actin	regulates	protein	0.60
HIPPO	regulates	gene	0.60
MT-ATP6	regulates	gene	0.60
AND	regulates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
GENES	regulates	gene	0.60
ALZHEIMER	regulates	gene	0.60
PI3K	regulates	gene	0.60
AKT	regulates	gene	0.60
MITOCHONDRIAL DYSFUNCTION	regulates	gene	0.60
DNA	regulates	gene	0.60
ATP	regulates	gene	0.60
Hippo Pathway	regulates	pathway	0.60
Neuron	regulates	cell_type	0.60
Hippocampus	expressed_in	brain_region	0.55
Neuron	expressed_in	cell_type	0.55

Incoming (19)

Source	Relation	Type	Str
PGC1α	regulates	protein	0.70
AND	regulates	gene	0.60
RNA	regulates	gene	0.60
MT-ATP6	regulates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
PI3K	regulates	gene	0.60
HIPPO	regulates	gene	0.60
AKT	regulates	gene	0.60
MITOCHONDRIAL DNA	regulates	gene	0.60
MITOCHONDRIAL DYSFUNCTION	regulates	gene	0.60
MT-ND4L	regulates	gene	0.60
ROS	regulates	gene	0.60
APOPTOSIS	regulates	gene	0.60
MST1	regulates	gene	0.60
OXIDATIVE STRESS	regulates	gene	0.60
ALZHEIMER	regulates	gene	0.60
GENES	regulates	gene	0.60
ATP	regulates	gene	0.60
DNA	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity