| Gene Symbol | NURR1 |
| Full Name | Nuclear Receptor Related 1 (NURR1) |
| Protein Type | Protein |
| Target Class | Protein |
| Function | NURR1 is an orphan nuclear receptor with ligand-independent activity: |
| Mechanism of Action | Prioritized from 1 SciDEX hypotheses, including: Programmable Neuronal Circuit Repair via Epigenetic CRISPR |
| Druggability | Low (0.50) |
| Clinical Stage | Phase I |
| Amino Acids | 598 aa |
| Exons | 8 |
| Pathways | Alpha-Synuclein, Autophagy, Er Stress, Synaptic Plasticity |
| UniProt ID | Search UniProt |
| Ensembl ID | ENSG00000153234 |
| GeneCards | NURR1 |
| Human Protein Atlas | NURR1 |
| Associated Diseases | Parkinson, Parkinson's disease, neurodegeneration |
| Known Drugs/Compounds | levodopa |
| Interactions | GFAP, LAMP1, LAMP2, GBA, CTSD, VMAT2 |
| SciDEX Target | View Target Profile |
| KG Connections | 208 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |