| Gene Symbol | TNFSF10 |
| Full Name | TNF Superfamily Member 10 (TNF-Related Apoptosis-Inducing Ligand) |
| Chromosome | 3q26.1 |
| Protein Family | TNF superfamily, Type II transmembrane proteins |
| Function | is a member of the tumor necrosis factor (TNF) superfamily that plays complex roles in cell death, immune surveillance, and neuroinflammation. |
| Molecular Weight | 32.5 kDa (monomer), ~97.5 kDa (homotrimer) |
| Amino Acids | 281 aa |
| Pathways | Apoptosis, Immune Response |
| UniProt ID | P50591 |
| Ensembl ID | ENSG00000117586 |
| GeneCards | TNFSF10 |
| Human Protein Atlas | TNFSF10 |
| Protein Length | 281 amino acids |
| Structure | Type II transmembrane protein with extracellular TNF homology domain |
| Cellular Location | Cell surface (membrane-bound) and soluble (cleaved form) |
| Associated Diseases | Als, Cancer, Carcinoma, Ms, Tumor |
| Interactions | TNFRSF1A, FYCO1, DR5, TRAIL, CASP8, TNF |
| KG Connections | 45 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |