| Gene Symbol | VDAC2 |
| Full Name | Voltage-Dependent Anion Channel 2 |
| Chromosome | 10q22.2 |
| Function | ### Mitochondrial Metabolite Transport |
| Primary Expression | Ubiquitous, high in brain, heart, skeletal muscle |
| Molecular Weight | 31.6 kDa |
| Amino Acids | 294 aa |
| Pathways | Autophagy, autophagy pathway, epigenetic regulation, mitophagy, oxidative stress response |
| UniProt ID | P45880 |
| NCBI Gene ID | 7417 |
| Ensembl ID | ENSG00000165637 |
| OMIM | 193245 |
| GeneCards | VDAC2 |
| Human Protein Atlas | VDAC2 |
| Open state (low voltage) | Conducts anions (ATP4-, ADP3-, Pi) and small metabolites, enabling oxidative phosphorylation |
| Associated Diseases | Cancer, Cardiovascular, Inflammation, Ischemia, Ms, Neurodegeneration |
| Known Drugs/Compounds | rapamycin |
| Interactions | AMPK, AMYLOID, APOPTOSIS, AR, ATF4, ATG |
| KG Connections | 211 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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