Scientific World Model

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Showing 1–50 of 217 pages matching "kinase"

⚙️ LRRK2 Kinase Activation and Endolysosomal Dysfunction in Parkinson's DiseaseKG

mechanism · 4,337 words · 28 hyp48 ana82 exp

🧬 PICK1 - Protein Interacting With C Kinase 1KG

gene · 3,315 words · 6 hyp7 ana2 exp

🧬 PAK3 — p21-Activated Kinase 3KG

gene · 3,177 words · 1 hyp2 ana

🔬 PAK2 Protein (p21-Activated Kinase 2)KG

protein · 3,160 words · 4 hyp7 ana1 exp

⚙️ WNK1 Kinase in NeurodegenerationKG

mechanism · 3,111 words · 279 hyp56 ana58 exp

⚙️ Tau Kinase Signaling Cascade in Alzheimer's DiseaseKG

mechanism · 3,059 words · 128 hyp49 ana56 exp

🧬 GSK3B Gene - Glycogen Synthase Kinase 3 BetaKG

gene · 3,026 words · 27 hyp14 ana

🔬 GSK3B (Glycogen Synthase Kinase 3 Beta)KG

protein · 2,976 words · 33 hyp17 ana

⚙️ Glycogen Synthase Kinase-3β (GSK-3β)KG

mechanism · 2,976 words · 11 hyp35 ana

🧬 PLAU Gene (Urokinase)KG

gene · 2,967 words · 19 hyp19 ana

🧬 LRRK2 — Leucine Rich Repeat Kinase 2KG

gene · 2,834 words · 43 hyp26 ana24 exp

🧬 PRKCD — Protein Kinase C DeltaKG

gene · 2,808 words · 4 hyp5 ana

🧬 PRKCG — Protein Kinase C GammaKG

gene · 2,761 words · 18 hyp7 ana1 exp

🧬 PDK4 (3-Phosphoinositide-Dependent Protein Kinase-4)KG

gene · 2,724 words · 24 hyp10 ana5 exp

🧬 CSNK1D - Casein Kinase 1 DeltaKG

gene · 2,701 words · 10 hyp3 ana

⚙️ Tau Kinase-Phosphatase Balance in Alzheimer's DiseaseKG

mechanism · 2,631 words · 31 hyp44 ana49 exp

🧬 MERTK - MER Tyrosine KinaseKG

gene · 2,621 words · 7 hyp5 ana1 exp

🧬 MAP3K4 — Mitogen-Activated Protein Kinase Kinase Kinase 4KG

gene · 2,598 words · 5 hyp7 ana2 exp

⚙️ SYK Kinase in Microglial Activation and Alzheimer's DiseaseKG

mechanism · 2,557 words · 71 hyp56 ana57 exp

🧬 AXL - AXL Receptor Tyrosine KinaseKG

gene · 2,512 words · 5 hyp6 ana

🧬 RIPK2 (Receptor-Interacting Serine/Threonine-Protein Kinase 2)KG

gene · 2,509 words · 2 hyp1 ana

🧬 GRK5 — G Protein-Coupled Receptor Kinase 5KG

gene · 2,476 words · 4 hyp8 ana

🧬 TYRO3 - TYRO3 Receptor Tyrosine KinaseKG

gene · 2,468 words · 7 hyp6 ana

🧬 GRK3 — G Protein-Coupled Receptor Kinase 3KG

gene · 2,456 words · 4 hyp8 ana

🔬 WEE1 Protein (WEE1 Kinase)KG

protein · 2,445 words · 6 hyp4 ana

🧬 LRRK2 (Leucine-Rich Repeat Kinase 2) — Comprehensive Gene ReviewKG

gene · 2,407 words · 5 hyp4 ana24 exp

💊 LRRK2 Kinase-Targeting TherapiesKG

therapeutic · 2,405 words · 38 hyp14 ana31 exp

🧬 CDK11 — Cyclin-Dependent Kinase 11KG

gene · 2,387 words · 3 hyp2 ana

🔬 LCK Protein (Lymphocyte-Specific Protein Tyrosine Kinase)KG

protein · 2,373 words · 4 hyp10 ana

🧬 PTK2B — Protein Tyrosine Kinase 2 Beta (Pyk2)KG

gene · 2,370 words · 12 hyp3 ana

⚙️ SYK Kinase in Microglial Activation and Alzheimer's DiseaseKG

mechanism · 2,366 words · 76 hyp57 ana56 exp

⚙️ LRRK2 Kinase Pathway in Parkinson's DiseaseKG

mechanism · 2,335 words · 22 hyp46 ana82 exp

🔬 Protein Kinase A (PKA) NeuronsKG

cell · 2,333 words · 10 hyp15 ana

⚙️ LRRK2→Kinase→Autophagy→PD Causal ChainKG

mechanism · 2,325 words · 13 hyp37 ana27 exp

🧬 PNKP - Polynucleotide Kinase 3'-PhosphataseKG

gene · 2,320 words · 3 hyp4 ana12 exp

🏥 Pantothenate Kinase-Associated Neurodegeneration (PKAN)KG

disease · 2,291 words · 457 hyp229 ana107 exp

🔬 Aurora Kinase C ProteinKG

protein · 2,281 words · 4 hyp6 ana

💊 Pantothenate Kinase-Associated Neurodegeneration (PKAN) TreatmentKG

therapeutic · 2,271 words · 280 hyp52 ana55 exp

🧬 CAMK2D — Calcium/Calmodulin-Dependent Kinase 2 DeltaKG

gene · 2,230 words · 6 hyp6 ana

🔬 PKR (Protein Kinase R)KG

protein · 2,153 words · 4 hyp7 ana

⚙️ Protein Kinase C Signaling PathwayKG

mechanism · 2,074 words · 72 hyp39 ana

🧬 CHEK2 — Checkpoint Kinase 2KG

gene · 2,022 words · 4 hyp3 ana

🧬 CHUK — IKK Alpha (IκB Kinase Alpha)KG

gene · 1,969 words · 13 hyp4 ana

🔬 GSK3B Protein (Glycogen Synthase Kinase 3 Beta)KG

protein · 1,959 words · 9 hyp8 ana

🧬 PRKCA — Protein Kinase C AlphaKG

gene · 1,953 words · 1 ana

⚙️ Protein Kinase C (PKC) Signaling in Parkinson's DiseaseKG

mechanism · 1,953 words · 66 hyp44 ana63 exp

🏥 Pantothenate Kinase-Associated Neurodegeneration (PKAN)KG

disease · 1,886 words · 458 hyp226 ana107 exp

🧬 PRKAA2 (AMPKα2) — AMP-Activated Protein Kinase Catalytic Subunit Alpha 2KG

gene · 1,883 words · 20 hyp11 ana1 exp

🧬 DGUOK — Deoxyguanosine KinaseKG

gene · 1,850 words · 4 hyp3 ana

🧬 MAP3K2 — Mitogen-Activated Protein Kinase Kinase Kinase 2KG

gene · 1,838 words · 5 hyp5 ana1 exp