Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about atg16l2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | ATG16L2 |
| Full Name | Autophagy Related 16 Like 2 |
| Chromosome | 11q13.2 |
| Function | is a gene located on chromosome 11q13. |
| UniProt ID | Q8N5L8 |
| NCBI Gene ID | 89849 |
| Ensembl ID | ENSG00000134133 |
| OMIM | 614678 |
| GeneCards | ATG16L2 |
| Human Protein Atlas | ATG16L2 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
ATG16L2["ATG16L2"]
ATG16L2 -->|"implicated in"| neurodegeneration["neurodegeneration"]
ATG16L2 ---|"associated"| Lupus["Lupus"]
ATG16L2 ---|"associated"| BECN1["BECN1"]
ATG16L2 ---|"associated"| ATG5["ATG5"]
ATG16L2 ---|"associated"| CDKN1B["CDKN1B"]
ATG16L2 ---|"associated"| ATG7["ATG7"]| Target | Relation | Type | Str |
|---|---|---|---|
| Lupus | associated_with | disease | 0.65 |
| BECN1 | associated_with | gene | 0.60 |
| ATG5 | associated_with | gene | 0.60 |
| CDKN1B | associated_with | gene | 0.60 |
| ATG7 | associated_with | gene | 0.60 |
| RUBCN | associated_with | gene | 0.60 |
| CYBB | associated_with | gene | 0.60 |
| LRRK2 | associated_with | gene | 0.60 |
| LC3 | associated_with | gene | 0.60 |
| MAP1LC3B | associated_with | gene | 0.60 |
| DRAM1 | associated_with | gene | 0.60 |
| MTORC1 | associated_with | gene | 0.60 |
| PHAGOCYTOSIS | associated_with | gene | 0.60 |
| AUTOPHAGY | associated_with | gene | 0.60 |
| DNA | associated_with | gene | 0.60 |
| IFN | associated_with | gene | 0.60 |
| Autophagy | associated_with | pathway | 0.60 |
| Mtor | associated_with | pathway | 0.60 |
| Immune Response | associated_with | pathway | 0.60 |
| Phagocytosis | associated_with | pathway | 0.60 |
| Adaptive Immunity | associated_with | pathway | 0.60 |
| benchmark_ot_ad_answer_key:ATG16L2 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ATG16L2 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||