GOT1

Understanding Entity Pages

This page aggregates everything SciDEX knows about GOT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

GOT1 is a gene implicated in neurodegeneration research. Key relationships include: associated with, activates, inhibits. Associated with Als, Carcinoma, Fibrosis. Connected to 49 entities in the SciDEX knowledge graph.

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graph TD
    GOT1["<b>GOT1</b>"]
    Carcinoma{"Carcinoma"}
    GOT1 -->|"associated with"| Carcinoma
    Fibrosis{"Fibrosis"}
    GOT1 -->|"activates"| Fibrosis
    Als{"Als"}
    GOT1 -->|"activates"| Als
    Ms{"Ms"}
    GOT1 -->|"activates"| Ms
    GOT1 -->|"inhibits"| Ms
    SQSTM1["SQSTM1"]
    GOT1 -->|"associated with"| SQSTM1
    GPT["GPT"]
    GOT1 -->|"associated with"| GPT
    ELAVL1["ELAVL1"]
    GOT1 -->|"associated with"| ELAVL1
    GPX4["GPX4"]
    GOT1 -->|"associated with"| GPX4
    ATG["ATG"]
    GOT1 -->|"associated with"| ATG
    BECLIN1["BECLIN1"]
    GOT1 -->|"activates"| BECLIN1
    P62["P62"]
    GOT1 -->|"associated with"| P62
    MIRNAS["MIRNAS"]
    MIRNAS -->|"inhibits"| GOT1
    style GOT1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0