GPT

Understanding Entity Pages

This page aggregates everything SciDEX knows about GPT: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Comprehensive gene page for GPT (Alanine Transaminase/ALT), an enzyme important for amino acid metabolism, liver function, and its relevance to neurodegenerative diseases through metabolic pathways.

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graph TD
    GPT["<b>GPT</b>"]
    Carcinoma{"Carcinoma"}
    GPT -->|"associated with"| Carcinoma
    Fibrosis{"Fibrosis"}
    GPT -->|"activates"| Fibrosis
    Als{"Als"}
    GPT -->|"activates"| Als
    Ms{"Ms"}
    GPT -->|"activates"| Ms
    ELAVL1["ELAVL1"]
    GPT -->|"associated with"| ELAVL1
    GPX4["GPX4"]
    GPT -->|"associated with"| GPX4
    ATG["ATG"]
    GPT -->|"associated with"| ATG
    BECLIN1["BECLIN1"]
    GPT -->|"activates"| BECLIN1
    P62["P62"]
    GPT -->|"associated with"| P62
    FTH1["FTH1"]
    GPT -->|"associated with"| FTH1
    MAP1LC3B["MAP1LC3B"]
    GPT -->|"associated with"| MAP1LC3B
    TGFB1["TGFB1"]
    GPT -->|"associated with"| TGFB1
    GOT1["GOT1"]
    GOT1 -->|"associated with"| GPT
    SQSTM1["SQSTM1"]
    SQSTM1 -->|"associated with"| GPT
    style GPT fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0